Dkk1 500 do kad

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05.06.2021 Dkk1 500 do kad

The gene view histogram is a graphical view of mutations across DKK1. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. Expression of DKK1 (DKK-1, SK) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.

13380 Ensembl ENSG00000107984 ENSMUSG00000024868 UniProt O94907 O54908 RefSeq (mRNA) NM_012242 NM_010051 RefSeq (protein) NP_036374 NP_034181 Location (UCSC) Chr 10: 52.31 – 52.32 Mb Chr 19: 30.55 – 30.55 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Dickkopf-related protein 1 is a protein that in humans is encoded by the DKK1 gene. Contents 1 Function 2 Interactions 3 Clinical

- 700 руб. До 200 кг. – 1 200 руб. Доставка по России - транспортными 1) Abcam product code ab ab61275 2) Abcam order reference number or product batch number GR64429 3) Description of the problem There is no specific band 4) Sample preparation: Split with RIPA Buffer Type of sample (whole cell lysates, fraction, recombinant protein…): whole cell lysates Lysis buffer RIPA Buffer with protease inhibitors Protease inhibitors: cocktail Phosphatase inhibitors DTT Na3NO4 … In transgenic Otx2 Dkk1/Dkk1 embryos, expression of Dkk1 from the Otx2 locus can rescue the migration defects of Otx2-deficient visceral endoderm cells.

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Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. Rabbit polyclonal DKK1 antibody. Validated in IHC and tested in Human. Cited in 15 publication(s).

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The high expression of DKK1 has as a result that mesenchymal stem cells do not differentiate to osteoblasts (Tian et al., 2003). Antibodies against DKK-1 (BHQ880) have shown encouraging results in patients with myeloma (Iyer et al., 2014), however their development seems to be currently discontinued. DKK-1 is a central regulator of osteoblast activity and osteoblastic bone metastasis and is likely dually dependent on the downregulation of microenvironment DKK-1 secretion from: (1) osteoblasts via tumor-produced ET-1; and (2) prostate cancer cells themselves. From: Bone Cancer, 2010. Download as PDF. The dickkopf protein encoded by DKK1 is an antagonist of the Wnt/β-catenin signalling pathway that acts by isolating the LRP6 co-receptor so that it cannot aid in activating the WNT signaling pathway. DKK1 was also demonstrated to antagonize the Wnt/β-catenin pathway via a reduction in β-catenin and an increase in OCT4 expression. DKN-01 is an immunotherapy that specifically reduces the levels of DKK1, a protein that is often elevated in several types of cancer.

DKK-1 was originally identified as a Xenopus head-forming molecule that behaves as an antagonist for Wnt signaling. DKK1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 258 amino acids (32-266 a.a) and having a molecular mass of 28.2kDa. DKK1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. The gene view histogram is a graphical view of mutations across DKK1. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. Dkk-1: Products.

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Summary of DKK1 (DKK-1, SK) expression in human tissue. muscle Adipose tissue Thymus Appendix Spleen Lymph node Tonsil 0 100 200 300 400 500 600

DKK1 overexpression is known for its pathological implications in osteoporosis, cancer, and neurodegeneration, suggesting the interaction with LRP5/6 as a potential therapeutic target Кола, д. 3, (Мурманское шоссе у КАД) (Ежедневно с 9:00 до 21:00) +7 (812) 602 61 21 +7 (800) 350 60 72 Бесплатно по территории России Play classic card games online with friends, against bots or compete globally with thousands of players. Free, no ads, sign-ups or downloads! Регистрация участника аукциона. Онлайн-аукцион по продаже антиквариата, старинных иностранных, а также монет России, банкнот и медалей приглашает продавцов и покупателей Результаты поиска Яндекс.Маркет по запросу — «Стульчик для кормления Peg-perego Tatamia Follow Me Paloma» — список товаров Результаты поиска Яндекс.Маркет по запросу — «Сменный чехол Peg-Perego» — список товаров В интернет-магазине Эрарта вы можете купить оригинал картины «Вдох-выдох», художник – Маша Трегубенко, жанр – Композиция, направление – Реализм. Get the best deals on Volvo Penta Complete Inboard Diesel Engines when you shop the largest online selection at eBay.com. Free shipping on many items | Browse your favorite brands | affordable prices.

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DKK1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 258 amino acids (32-266 a.a) and having a molecular mass of 28.2kDa. DKK1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. The gene view histogram is a graphical view of mutations across DKK1. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. Dkk-1: Products. Dkk-1 (Dickkopf related protein 1) is a secreted antagonist of Wnt/beta-Catenin signaling.